The third EUPON Meeting
Update on Optic Nerve Degeneration
A European Network

14–15th April 2018, Düsseldorf, Germany


Welcome to

The EUPON Meeting 2018
Update on Optic Nerve Degeneration: a European Network

The third annual EUPON meeting will be held on Apr 14–15th 2018 in Düsseldorf. EUPON is a unique interdisciplinary scientific meeting focusing on diseases of the optic nerve and retina from both an ophthalmologic and a neurologic perspective. This year’s meeting covers nine main topics which will be covered from the preclinical, diagnostic and therapeutic point of view: Optic neuritis and multiple sclerosis, neuromyelitis spectrum disorders, preclinical retinal imaging of mice and rats, hereditary optic neuropathies, glaucoma, retinal diseases affecting the optic nerve, standardization of retinal imaging (quality control criteria and reporting guidelines), anterior ischemic optic neuropathy, and pseudotumor cerebri syndrome. We have tried to put a special focus on including not only cutting edge lectures on the clinical state of the art but also integrating the relevant translational aspects of basic science research in the field.

We hope to see you in Düsseldorf for EUPON 2018 and are looking forward to exciting scientific talks and interdisciplinary discussions with you.

Kind regards,

Philipp Albrecht, Wolf Lagrèze, Rainer Guthoff and Orhan Aktas


Program 14th of April 2018

8:30–8:45 Registration / Coffee
Optic Neuritis / MS
Chairs: Wolf Lagrèze, Friedemann Paul
8:50–9:00 Welcome
Hans-Peter Hartung, Düsseldorf
9:00–9:20 Pathophysiology of ganglion cell loss in EAE
Kira Pichi, Heidelberg
9:20–9:40 Diagnostic approaches assessing the visual system in MS
Friedemann Paul, Berlin
9:40–10:00 The value of VEP and mfVEP in MS
Letizia Leocani, Milan
10:00–10:20 MRI imaging of the visual system in MS
Inigo Gabilondo, Bilbao
10:20–10:40 Coffee break
10:40–11:00 The thickness of the inner nuclear layer (INL) and disease activity in MS
Benjamin Knier, München
11:00–11:20 Reexamining the INL in MS: Findings and relevance of INL thickness in a multicenter study
Lisanne Balk, Amsterdam
11:20–11:40 The prognostic value of (mf)VEP and OCT in ON and MS
Jette Frederiksen Lautrup Battistini, Kopenhagen
11:40–12:00 Therapeutic approaches to Optic Neuritis
Wolf Lagrèze, Freiburg
12:00–13:00 Lunch
Chairs: Christian van Oterendorp, Ullrich Wüllner
13:00–13:20 Animal models for AION and their application to translational research
Chantal Dysli, Bern
13:20–13:40 An update on the diagnostic approaches for AION
Helmut Wilhelm, Tübingen
13:40–14:00 The therapeutic approaches for AION
Christian van Oterendrop, Göttingen
14:00–14:20 Current opinion and data on the pathopyhsiology and therapeutic options of pseudotumor cerebri syndrome
Ullrich Wüllner, Bonn
14:20–14:40 Diagnostic approaches to pseudotumor cerebri syndrome
Wolf Lagrèze, Freiburg
14:40–15:10 Coffee break
Chairs: Orhan Aktas, Hans-Peter Hartung
15:10–15:30 Retinal imaging as diagnostic parameter for NMOSD
Joachim Havla, München
15:30–15:50 Visual evoked potentials in NMOSD
Marius Ringelstein, Düsseldorf
15:50–16:10 Established and emerging therapeutic strategies for NMOSD
Orhan Aktas, Düsseldorf
The interface: Retinal diseases affecting brain/optic nerve and vice versa
Chairs: Rainer Guthoff, Elmar Pinkhardt
16:10–16:30 Systemic diseases affecting retina and visual system - Neurodegeneration in Diabetic Retinopathy
Rainer Guthoff, Düsseldorf
16:30–16:50 Retinal findings in Parkinson’s disease and other neurodegenerative diseases
Elmar Pinkhardt, Ulm
16:50–17:10 Cerebrovascular disease and the retina – posterior cerebral artery infarction
John-Ih Lee, Düsseldorf


Program 15th of April 2018

Preclinical Session (Mice and Rats)
Chairs: Philipp Albrecht, Mathias Seeliger
9:00–9:20 The role of microglia during experimental autoimmune encephalomyelitis/optic neuritis
Marta Jordao, Freiburg
9:20–9:40 Retinal imaging in EAE for translational neuroprotection studies
Philipp Albrecht, Düsseldorf
9:40–10:00 Diffusion tensor imaging of the visual system in EAE
Sven Schippling, Zürich
10:00–10:20 Translation EAE to MS: Unsuspected effects of 4-Aminopyridine
Michael Dietrich, Düsseldorf
10:20–10:50 Coffee break
10:50–11:10 Retinal imaging in neurodegenerative models
Janos Groh, Würzburg
11:10–11:30 Preclinical models for retinopathies and their application in translational research
Mathias Seeliger, Tübingen
Chairs: David Garway-Heath, Elmar Pinkhardt
11:30–11:50 Insights from preclinical models for glaucoma and retinal ganglion cell damage
Dietmar Fischer, Düsseldorf
11:50–12:10 An overview on the diagnostic criteria and procedures as well as therapeutic options for glaucoma
David Garway-Heath, London
12:10–13:10 Lunch
Hereditary optic neuropathies
Chairs: Piero Barboni, Patrick Yu Wai Man
13:10–13:30 Preclinical models of hereditary optic neuropathies
Bernd Wissinger, Tübingen
13:30–13:50 Diagnostic approaches to hereditary optic neuropathies
Piero Barboni, Milan
13:50–14:20 Coffee break
14:30–14:50 Therapeutic options for hereditary optic neuropathies
Patrick Yu Wai Man, Cambridge
14:50–15:10 The APOSTEL recommendations for reporting of OCT studies
Philipp Albrecht, Düsseldorf


Invited Speakers

  • Aktas, Orhan – Düsseldorf
  • Albrecht, Philipp – Düsseldorf
  • Balk, Lisanne – Amsterdam
  • Barboni, Piero – Milan
  • Dietrich, Michael – Düsseldorf
  • Dysli, Chantal – Bern
  • Fischer, Dietmar – Düsseldorf
  • Frederiksen, Jette Lautrup - Kopenhagen
  • Gabilondo, Inigo – Bilbao
  • Garway-Heath, David – London
  • Groh, Janos – Würzburg
  • Guthoff, Rainer – Düsseldorf
  • Hartung, Hans-Peter – Düsseldorf
  • Havla, Joachim – München
  • Jordao, Marta – Freiburg
  • Knier, Benjamin – München
  • Lagrèze, Wolf – Freiburg
  • Lee, John-Ih – Düsseldorf
  • Leocani, Letizia – Milan
  • Oterendrop, Christian van – Göttingen
  • Paul, Friedemann – Berlin
  • Pichi, Kira – Heidelberg
  • Pinkhardt, Elmar – Ulm
  • Ringelstein, Marius – Düsseldorf
  • Schippling, Sven – Zürich
  • Seeliger, Mathias – Tübingen
  • Wilhelm, Helmut – Tübingen
  • Wissinger, Bernd – Tübingen
  • Wüllner, Ullrich – Bonn
  • Yu Wai Man, Patrick – Cambridge

General Information


EUPON inspires European multidisciplinary collaborations to further the knowledge in ophthalmological and neurological optic nerve pathologies.


To be a European reference and lead international efforts in diagnostic, therapeutic and research strategies involving optic nerve.

Target audience

Ophthalmologists, neurologists, engineers working in biomedicine, orthoptists, optometrists, nurses, medical technicians


Application for CME-certification pending.

Registration fees (VAT included)

Regular: 200,– Euro
Students: free of charge (student ID required)

Registration fee includes conference documents and catering.

Cancellation Terms

Cancellation has to be submitted in written form to the company jottkaa GmbH.
until 14th March = 50%
from 15th March = no refund

Substitute participants are accepted.

Organized By / Venue

Organized By

Priv. Doz. Dr. Philipp Albrecht
Consultant Neurologist
University Hospital Düsseldorf / Dept. of Neurology
Phone: +49 (0) 211 / 810 84 75

Wolf Lagrèze, Rainer Guthoff und Orhan Aktas


University Hospital Düsseldorf / Universitätsklinikum Düsseldorf
Gebäude 13.55, Hörsaal 13 B
Universitätsstraße 1
40225 Düsseldorf

View on Google Maps

We thank our sponsors

Gold sponsor

Novartis Pharma GmbH

10.000,- €

Roche Pharma AG

10.000,- €

Santhera (Germany) GmbH

10.000,- €

Silver sponsor

Biogen GmbH

6.000,- €

Heidelberg Engineering GmbH

5.000,- €

Sanofi Genzyme

5.000,- €

Teva GmbH

7.000,- €


Carl Zeiss Meditec GmbH

1.500,- €

Merck KGaA

2.000,- €

Project Manager

Congress Office
jottkaa Projekt.Konzept GmbH
Inken Kienzle
Phone: +49 (0) 221 / 570 85 54 - 0


Online Registration